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10.1093/jxb/ers043 11 FeechanA.KwonE.YunB

Research Square PrintNovember 10th, 2022 Research Square PrintNovember 4th, 2022

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Accumulating findings further suggest that intestinal inflammation may trigger misfolding of -synuclein within enteric neurons, enabling its propagation to the brainstem via vagal pathways and providing a mechanistic link between gut pathology and dopaminergic neurodegeneration

In addition to enhanced diagnostic capabilities, emerging environmental pollutantsparticularly MPshave been proposed as potential contributors to this rapid escalation 31